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Ndhlovu, Lishomwa

One or more keywords matched the following properties of Ndhlovu, Lishomwa

Property	Value
overview	Our research is dedicated to understanding how HIV affects the immune system and how this will inform on strategies to prevent, slow or eliminate HIV infection and optimize quality of life outcomes.

One or more keywords matched the following items that are connected to Ndhlovu, Lishomwa

Item Type	Name
Academic Article	Identification of human endogenous retrovirus-specific T cell responses in vertically HIV-1-infected subjects.
Academic Article	IL-2 immunotherapy to recently HIV-1 infected adults maintains the numbers of IL-17 expressing CD4+ T (T(H)17) cells in the periphery.
Academic Article	Strong human endogenous retrovirus-specific T cell responses are associated with control of HIV-1 in chronic infection.
Academic Article	HIV-1 infection abrogates CD8+ T cell mitogen-activated protein kinase signaling responses.
Academic Article	Plasma monocyte chemoattractant protein-1 and tumor necrosis factor-a levels predict the presence of coronary artery calcium in HIV-infected individuals independent of traditional cardiovascular risk factors.
Academic Article	Age-related expansion of Tim-3 expressing T cells in vertically HIV-1 infected children.
Academic Article	Albuminuria as a marker of cardiovascular risk in HIV-infected individuals receiving stable antiretroviral therapy.
Academic Article	Monocytes expand with immune dysregulation and is associated with insulin resistance in older individuals with chronic HIV.
Academic Article	Galectin-9 is rapidly released during acute HIV-1 infection and remains sustained at high levels despite viral suppression even in elite controllers.
Academic Article	Soluble T cell immunoglobulin mucin domain 3 is shed from CD8+ T cells by the sheddase ADAM10, is increased in plasma during untreated HIV infection, and correlates with HIV disease progression.
Academic Article	IL-1? enriched monocytes mount massive IL-6 responses to common inflammatory triggers among chronically HIV-1 infected adults on stable anti-retroviral therapy at risk for cardiovascular disease.
Academic Article	LINE-1 retrotransposable element DNA accumulates in HIV-1-infected cells.
Academic Article	The role of HIV and monocytes/macrophages in adipose tissue biology.
Academic Article	Activation associated ERK1/2 signaling impairments in CD8+ T cells co-localize with blunted polyclonal and HIV-1 specific effector functions in early untreated HIV-1 infection.
Academic Article	T cell Ig and mucin domain-containing protein 3 is recruited to the immune synapse, disrupts stable synapse formation, and associates with receptor phosphatases.
Academic Article	Reduced CD14 expression on classical monocytes and vascular endothelial adhesion markers independently associate with carotid artery intima media thickness in chronically HIV-1 infected adults on virologically suppressive anti-retroviral therapy.
Academic Article	Albuminuria is associated with elevated acute phase reactants and proinflammatory markers in HIV-infected patients receiving suppressive combination antiretroviral therapy.
Academic Article	Characterization of lipid composition and high-density lipoprotein function in HIV-infected individuals on stable antiretroviral regimens.
Academic Article	Non-Classical Monocytes and Monocyte Chemoattractant Protein-1 (MCP-1) Correlate with Coronary Artery Calcium Progression in Chronically HIV-1 Infected Adults on Stable Antiretroviral Therapy.
Academic Article	CD4/CD8 Ratio Predicts Peripheral Fat in HIV-Infected Population.
Academic Article	Oxidative mitochondrial DNA damage in peripheral blood mononuclear cells is associated with reduced volumes of hippocampus and subcortical gray matter in chronically HIV-infected patients.
Academic Article	Human Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation.
Academic Article	High 25-hydroxyvitamin D is associated with unexpectedly high plasma inflammatory markers in HIV patients on antiretroviral therapy.
Academic Article	Plasminogen Activator Inhibitor-1 Predicts Negative Alterations in Whole-Body Insulin Sensitivity in Chronic HIV Infection.
Academic Article	TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection.
Academic Article	Serum amyloid P (SAP) is associated with impaired brachial artery flow-mediated dilation in chronically HIV-1 infected adults on stable antiretroviral therapy.
Academic Article	Atazanavir use and carotid intima media thickness progression in HIV: potential influence of bilirubin.
Academic Article	Strategies to target non-T-cell HIV reservoirs.
Academic Article	Elevation of Non-Classical (CD14+/lowCD16++) Monocytes Is Associated with Increased Albuminuria and Urine TGF-?1 in HIV-Infected Individuals on Stable Antiretroviral Therapy.
Academic Article	Non-classical monocytes predict progression of carotid artery bifurcation intima-media thickness in HIV-infected individuals on stable antiretroviral therapy.
Academic Article	Comparative DNA Methylation Profiling Reveals an Immunoepigenetic Signature of HIV-related Cognitive Impairment.
Academic Article	Improved Cognitive Performance and Reduced Monocyte Activation in Virally Suppressed Chronic HIV After Dual CCR2 and CCR5 Antagonism.
Academic Article	Normalization of Soluble CD163 Levels After Institution of Antiretroviral Therapy During Acute HIV Infection Tracks with Fewer Neurological Abnormalities.
Academic Article	Cenicriviroc inhibits trans-endothelial passage of monocytes and is associated with impaired E-selectin expression.
Academic Article	Red blood cell distribution width as an easily measurable biomarker of persistent inflammation and T cell dysregulation in antiretrovirally treated HIV-infected adults.
Academic Article	Elevated cerebrospinal fluid Galectin-9 is associated with central nervous system immune activation and poor cognitive performance in older HIV-infected individuals.
Academic Article	Ultra-Deep Sequencing Analysis on HIV Drug-Resistance-Associated Mutations Among HIV-Infected Individuals: First Report from the Philippines.
Academic Article	Anti-a4?7 therapy targets lymphoid aggregates in the gastrointestinal tract of HIV-1-infected individuals.
Academic Article	Impact of Myeloid Reservoirs in HIV Cure Trials.
Academic Article	Galectin-9 Mediates HIV Transcription by Inducing TCR-Dependent ERK Signaling.
Academic Article	PD-1+ and TIGIT+ CD4 T Cells Are Associated With Coronary Artery Calcium Progression in HIV-Infected Treated Adults.
Academic Article	Harvard HIV and Aging Workshop: Perspectives and Priorities from Claude D. Pepper Centers and Centers for AIDS Research.
Academic Article	Regional brain volumetric changes despite 2 years of treatment initiated during acute HIV infection.
Academic Article	Short Communication: Metformin Reduces CD4 T Cell Exhaustion in HIV-Infected Adults on Suppressive Antiretroviral Therapy.
Academic Article	Mitochondrial oxidative phosphorylation in peripheral blood mononuclear cells is decreased in chronic HIV and correlates with immune dysregulation.
Academic Article	Changes in gastrointestinal microbial communities influence HIV-specific CD8+ T-cell responsiveness to immune checkpoint blockade.
Academic Article	Associations Between Plasma Immunomodulatory and Inflammatory Mediators With VACS Index Scores Among Older HIV-Infected Adults on Antiretroviral Therapy.
Academic Article	Impact of HIV-1 infection on the IGF-1 axis and angiogenic factors in pregnant Cameroonian women receiving antiretroviral therapy.
Academic Article	Geriatric Syndromes in Older Adults Living with HIV and Cognitive Impairment.
Academic Article	Comparative DNA methylomic analyses reveal potential origins of novel epigenetic biomarkers of insulin resistance in monocytes from virally suppressed HIV-infected adults.
Academic Article	Frailty Is Associated With Insulin Resistance in Chronic Human Immunodeficiency Virus Infection.
Academic Article	Plasma inflammatory biomarkers link to diffusion tensor imaging metrics in virally suppressed HIV-infected individuals.
Academic Article	Lower Interferon Regulatory Factor-8 Expression in Peripheral Myeloid Cells Tracks With Adverse Central Nervous System Outcomes in Treated HIV Infection.
Academic Article	FOXP3 expressing CD127lo CD4+ T cells inversely correlate with CD38+ CD8+ T cell activation levels in primary HIV-1 infection.
Academic Article	T cell responses to human endogenous retroviruses in HIV-1 infection.
Academic Article	Conferral of enhanced natural killer cell function by KIR3DS1 in early human immunodeficiency virus type 1 infection.
Academic Article	High CD8+ T cell activation marks a less differentiated HIV-1 specific CD8+ T cell response that is not altered by suppression of viral replication.
Academic Article	Interleukin-10-secreting T cells define a suppressive subset within the HIV-1-specific T-cell population.
Academic Article	Suppression of HIV-1 plasma viral load below detection preserves IL-17 producing T cells in HIV-1 infection.
Academic Article	Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection.
Concept	HIV Infections
Grant	Reversal of Adaptive Immune Dysfunction in Shock and Kill HIV Cure Strategies
Grant	Modulating Tim-3 to control HIV infection
Grant	Effects of Human Galectin-9 on the CNS HIV Reservoir
Grant	Effects of HIV SIV on unconventional T cells in immunity to M. tuberculosis in pre adolescents
Grant	Host Glycomic Modulation of HIV-associated Neuro-inflammation During Viral Suppression
Grant	Monocytes and HIV CNS Reservoirs in Super Acute HIV Infection
Academic Article	Short Communication: Carotid Artery Plaque Burden in HIV Is Associated with Soluble Mediators and Monocytes.
Academic Article	Impact of Cannabis Use on Brain Structure and Function in Suppressed HIV Infection.
Academic Article	Effects of Brief Adjunctive Metformin Therapy in Virologically Suppressed HIV-Infected Adults on Polyfunctional HIV-Specific CD8 T Cell Responses to PD-L1 Blockade.
Academic Article	Increased Monocyte Inflammatory Responses to Oxidized LDL Are Associated with Insulin Resistance in HIV-Infected Individuals on Suppressive Antiretroviral Therapy.
Academic Article	Hiding in plain sight - platelets, the silent carriers of HIV-1.
Academic Article	Genome-wide DNA methylation profiling of peripheral blood reveals an epigenetic signature associated with severe COVID-19.
Academic Article	Next-Generation Human Cerebral Organoids as Powerful Tools To Advance NeuroHIV Research.
Academic Article	Glycolysis downregulation is a hallmark of HIV-1 latency and sensitizes infected cells to oxidative stress.
Academic Article	Antibody-based CCR5 blockade protects Macaques from mucosal SHIV transmission.
Academic Article	Plasma galectin-9 as a predictor of adverse non-AIDS events in persons with chronic HIV during suppressive antiretroviral therapy.
Academic Article	Abrupt and altered cell-type specific DNA methylation profiles in blood during acute HIV infection persists despite prompt initiation of ART.
Academic Article	Candidate host epigenetic marks predictive for HIV reservoir size, responsiveness to latency reversal, and viral rebound.
Academic Article	Siglec-9 defines and restrains a natural killer subpopulation highly cytotoxic to HIV-infected cells.
Academic Article	Immunologic Change over 72 Weeks Following Raltegravir- Versus Efavirenz-Based Therapy in HIV/HCV-Coinfected Individuals in Vietnam.
Academic Article	Human galectin-9 promotes the expansion of HIV reservoirs in vivo in humanized mice.
Academic Article	HIV viral transcription and immune perturbations in the CNS of people with HIV despite ART.
Academic Article	Mucosal-homing natural killer cells are associated with aging in persons living with HIV.
Academic Article	Elevated Cerebrospinal Fluid Anti-CD4 Autoantibody Levels in HIV Associate with Neuroinflammation.
Academic Article	Expression profiles of miR3181 and miR199a in plasma and placenta of virally suppressed HIV-1 infected Cameroonian pregnant women at delivery.
Academic Article	Circulating brain-derived extracellular vesicles expressing neuroinflammatory markers are associated with HIV-related neurocognitive impairment.
Academic Article	Brain volumetrics differ by Fiebig stage in acute HIV infection.
Academic Article	Plasma CD16+ Extracellular Vesicles Associate with Carotid Artery Intima-Media Thickness in HIV+ Adults on Combination Antiretroviral Therapy.
Academic Article	Individual Differences in CD4/CD8 T-Cell Ratio Trajectories and Associated Risk Profiles Modeled From Acute HIV Infection.
Academic Article	Plasma extracellular vesicles and cell-free mitochondrial DNA are associated with cognitive dysfunction in treated older adults with HIV.
Academic Article	Biotypes of Central Nervous System Complications in People With Human Immunodeficiency Virus: Virology, Immunology, and Neuropathology.
Academic Article	Increased transmigration of intermediate monocytes associated with atherosclerotic burden in people with HIV on antiretroviral therapy.
Academic Article	Host Immunity to Mycobacterium tuberculosis Infection Is Similar in Simian Immunodeficiency Virus (SIV)-Infected, Antiretroviral Therapy-Treated and SIV-Na?ve Juvenile Macaques.
Academic Article	Multiplex Analysis of Cytokines and Chemokines in Persons Aging With or Without HIV.
Academic Article	Distinct mucosal and systemic immunological characteristics in transgender women potentially relating to HIV acquisition.
Academic Article	Elevated Galectin-9 across the human brain correlates with HIV neuropathology and detrimental cognitive states.
Academic Article	Cell-type specific impact of metformin on monocyte epigenetic age reversal in virally suppressed older people living with HIV.
Academic Article	Soluble biomarkers of HIV-1-related systemic immune activation are associated with high plasma levels of growth factors implicated in the pathogenesis of Kaposi sarcoma in adults.
Academic Article	HIV-1 Remission: Accelerating the Path to Permanent HIV-1 Silencing.
Academic Article	The latent HIV reservoir: current advances in genetic sequencing approaches.

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HIV Infections

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